In Vitro Antimicrobial Activity of Camel Urine Lactoferrin
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Page Numbers:
495-504
Digital Object Identifier:
10.58578/kijst.v2i3.7706
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Authors:
K. A. Ahmad1, M. S. Jada2, A. U. Wurochekke3 
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Authors retain copyright and grant the journal right of first publication.
Main Article Content
Abstract
Lactoferrin, an iron-binding glycoprotein found in various bodily fluids, is widely recognized for its broad-spectrum antimicrobial properties. This study evaluates the in vitro antibacterial and antifungal activity of lactoferrin isolated from camel urine against selected microbial strains. The purified lactoferrin demonstrated notable antibacterial efficacy, producing zones of inhibition ranging from 12–19 mm against Staphylococcus aureus, 10–16 mm against Bacillus subtilis, and 13–21 mm against Escherichia coli. Additionally, antifungal activity was observed against Candida albicans, with inhibition zones ranging from 11–18 mm. The antimicrobial mechanisms are attributed to iron sequestration and disruption of microbial cell membranes in bacteria, and inhibition of fungal growth via interference with cell wall synthesis and membrane integrity. These findings underscore the potential of camel urine-derived lactoferrin as a natural antimicrobial agent and contribute to the growing body of research exploring its biochemical and therapeutic properties.
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Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
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