Optimasi Formulasi Basis Krim melalui Variasi Perbandingan Jumlah Asam Stearat dan Trietanolamin Optimization of Cream Base Formulation through Variation in the Ratio of Stearic Acid and Triethanolamine
Main Article Content
Abstract
Cream is a commonly used cosmetic formulation known for its high stability, largely due to the presence of emulsifiers in its oil and water phases, such as stearic acid and triethanolamine. Emulsifiers play a crucial role in maintaining the physical stability of the formulation. This study aims to optimize cream formulations by varying the ratios of stearic acid to triethanolamine, evaluated based on smoothness and adhesiveness parameters. The tested ratio variations included 5/2; 5/2.5; 5/3; 5/3.5; 5/4; 10/2; 10/2.5; 10/3; 10/3.5; 10/4; 15/2; 15/2.5; 15/3; 15/3.5; 15/4; 20/2; 20/2.5; 20/3; 20/3.5; and 20/4, with each formulation tested in triplicate. The results indicated that several combinations met the required standards for smoothness and adhesiveness, including 5/2; 10/2.5; 10/3; 10/3.5; 10/4; 15/2; 15/2.5; 15/3; 15/3.5; 15/4; 20/2.5; and 20/3. Further analysis revealed a strong correlation between smoothness, adhesiveness, and viscosity, with viscosity being directly influenced by the amounts of stearic acid and triethanolamine in the formulation. This study produced a base cream formulation that may serve as a reference for further development, including active ingredient incorporation, quality testing, and evaluation of other physical properties.
Downloads
Citation Metrics & Similar Scopus Articles
-
Xu J. (2027)The Band Structure of In-Plane Elastic Cracked Phononic Crystals Based on the Local RBF Collocation MethodAdvances in Applied Mathematics and Mechanics, 19(1), 397-417
-
Shiryazdi R.S. (2027)Assessing performances of pattern informatics method variants: a comparative analysis in Zagros, IranIranian Journal of Geophysics, 20(3), 65-80
-
Agarwala B.K. (2027)SIZE-STRUCTURED SUCCESSION AND OPTIMISATION IN APHID PREDATOR GUILDS: A SYSTEMATIC REVIEWIndian Journal of Entomology, 89(2), 421-428
Article Details

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
References
Ansel C, Allen LV, P. N. (2005). Pharmaceutical dosage form and Drug delivery system. B.I Publications, 70(3), 193–243.
Cahyati, A. N., Ekowati, D., & Harjant, R. (2015). Optimasi Kombinasi Asam Stearat dan Trietanolamin dalam Formula Krim Ekstrak Daun Legetan (Spilanthes acmella L.) sebagai Antioksidan secara Simplex Lattice Design Optimization of The Combination Stearic Acid and Trietanolamine in A Cream Formulation Extr. Maret, 12(1), 60–69. http://farmasiindonesia.setiabudi.ac.id/
Chauhan, L., & Gupta, S. (2020). Creams: A Review on Classification, Preparation Methods, Evaluation and its Applications. Journal of Drug Delivery and Therapeutics, 10(5-s), 281–289. https://doi.org/10.22270/jddt.v10i5-s.4430
Djiobie Tchienou, G. E., Tsatsop Tsague, R. K., Mbam Pega, T. F., Bama, V., Bamseck, A., Dongmo Sokeng, S., & Ngassoum, M. B. (2018). Multi-response optimization in the formulation of a topical cream from natural ingredients. Cosmetics, 5(1), 1–14. https://doi.org/10.3390/cosmetics5010007
Gyawali, R., Paudel, N., Shrestha, S., & Silwal, A. (2016). Formulation and Evaluation of Antibacterial and Antioxidant Polyherbal Lotion. Journal of Institute of Science and Technology, 21(1), 148–156. https://doi.org/10.3126/jist.v21i1.16067
Huda, N., Sindi, C., Amelia Kusmawan, Z., & Sinaga, H. (2022). Formulasi Sediaan Krim Ekstrak Etanol Kulit Buah Kakao (Theobroma cacao L.) sebagai Antioksidan. Jurnal Biogenerasi, 7(1), 163–170. https://doi.org/10.30605/biogenerasi.v7i1.1701
Jiménez Soriano, M. M., Fresno Contreras, M. J., & Sellés Flores, E. (2001). Development of a cream from a self-emulsifying base and moisturizing actives. Farmaco, 56(5–7), 513–522. https://doi.org/10.1016/S0014-827X(01)01087-4
Lestari, F. A., Hajrin, W., & Hanifa, N. I. (2020). Optimasi Formula Krim Ekstrak Daun Katuk (Sauropus Androgynus) Variasi Konsentrasi Asam Stearat, Trietanolamin, dan Gliserin. Jurnal Kefarmasian Indonesia, 10(2), 110–119. https://doi.org/10.22435/jki.v10i2.2496
Lumentut, N., Edi, H. J., & Rumondor, E. M. (2020). Formulasi dan Uji Stabilitas Fisik Sediaan Krim Ekstrak Etanol Kulit Buah Pisang Goroho (Musa acuminafe L.) Konsentrasi 12.5% Sebagai Tabir Surya. Jurnal MIPA, 9(2), 42. https://doi.org/10.35799/jmuo.9.2.2020.28248
Mudhana, A. R., & Pujiastuti, A. (2021). Pengaruh Trietanolamin Dan Asam Stearat Terhadap Mutu Fisik Dan Stabilitas Mekanik Krim Sari Buah Tomat. Indonesian Journal of Pharmacy and Natural Product, 4(2), 113–122. https://doi.org/10.35473/ijpnp.v4i2.1342
Paneo, M. A., Tungadi, R., Thomas, N., Ramadhani, F. N., & Mumtazah, N. (2024). Formulasi, Karakterisasi, dan Evaluasi Sediaan Krim Antosianin Berbasis Fitosom. Jurnal Farmasi Teknologi Sediaan Dan Kosmetika, 1(3), 64–76. https://doi.org/10.70075/jftsk.v1i3.78
Pratiwi, P. D., & Arnas, D. L. (2024). Aplikasi Simplex Lattice Design untuk Optimasi Emulgator dalam Krim Minyak Atsiri Kulit Jeruk Manis. Sinteza, 4(2), 85–93. https://doi.org/10.29408/sinteza.v4i2.26539
Rostami, M., Farzaneh, V., Boujmehrani, A., Mohammadi, M., & Bakhshabadi, H. (2014). Optimizing the extraction process of sesame seed’s oil using response surface method on the industrial scale. Industrial Crops and Products, 58, 160–165. https://doi.org/10.1016/j.indcrop.2014.04.015
Saryanti, D., Setiawan, I., & Safitri, R. A. (2019). Optimasi Asam Stearat Dan Tea Pada Formula Sediaan Krim Ekstrak Kulit Pisang Kepok (Musa paradisiaca L.). Jurnal Riset Kefarmasian Indonesia, 1(3), 225–237. https://doi.org/10.33759/jrki.v1i3.44
Suardana, I. M., Suhendra, L., & Wrasiati, L. P. (2020). Pengaruh Variasi Nilai Hydrophylic-lipophylic balance dan Suhu terhadap Karakteristik Sediaan Krim. Jurnal Rekayasa Dan Manajemen Agroindustri, 8(2), 189. https://doi.org/10.24843/jrma.2020.v08.i02.p04
Tungadi, R., Sy. Pakaya, M., & D.as’ali, P. W. (2023). Formulasi dan Evaluasi Stabilitas Fisik Sediaan Krim Senyawa Astaxanthin. Indonesian Journal of Pharmaceutical Education, 3(1), 117–124. https://doi.org/10.37311/ijpe.v3i1.14612
Weerapol, Y., Limmatvapirat, S., Nunthanid, J., & Sriamornsak, P. (2014). Self-nanoemulsifying drug delivery system of nifedipine: Impact of hydrophilic-lipophilic balance and molecular structure of mixed surfactants. AAPS PharmSciTech, 15(2), 456–464. https://doi.org/10.1208/s12249-014-0078-y
Yakub, J., & Setyani, W. (2023). Optimization of Stearic Acid and Triethanolamine in The Antibacterial Cream Staphylococcus aureus Ethanol Extract of Papaya Seeds (Carica papaya L.): Factorial Design Method. Journal of Pharmaceutical Sciences and Community, 20(1), 1–9. https://doi.org/10.24071/jpsc.002396
Yusuf Supriadi, & Nurbik Khoirin. (2022). Formulation and Evaluation of Grape Seed Oil (Vitis Vinifera, L) Facial Cream with Variations in The Concentration of Stearic Acid as an Emulsifier. Journal of Health Sciences and Medical Development, 1(01), 20–30. https://doi.org/10.56741/hesmed.v1i01.32
Yuwanda, A., Rahmawati, D., & Sukma Anjani, F. (2023). Formulasi Dan Evaluasi Aktivitas Antioksidan Pada Sediaan Krim Wajah dari Ekstrak Etanol Daun Pegagan (Centella Asiatica L.). Journal of Pharmacy and Halal Studies, 1(1), 9–16. https://doi.org/10.70608/p02dqz05






















