Tinjauan Literatur tentang Faktor Risiko, Pencegahan, dan Penanganan Palatoskizis (Celah Langit-Langit) A Literature Review on Risk Factors, Prevention, and Management of Palatoschisis (Cleft Palate)
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Page Numbers:
3375-3385
Digital Object Identifier:
10.58578/tsaqofah.v5i4.6299
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Authors:
Bismi Rahma Firna1, Yusni Atifah2 
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Authors retain copyright and grant the journal right of first publication.
Main Article Content
Abstract
Palatoschisis is a congenital craniofacial anomaly with significant clinical and social implications, particularly in developing countries where prevention and management efforts continue to face numerous challenges. This study aims to systematically review the scientific literature on risk factors, early detection methods, and management approaches for palatoschisis. A systematic literature review was conducted based on ten scholarly articles published in the past ten years, sourced from PubMed, ScienceDirect, and Google Scholar. Inclusion criteria consisted of articles in English or Indonesian that addressed the etiology, diagnosis, and treatment of palatoschisis. Thematic analysis was applied to categorize findings into key thematic areas. The review identified major risk factors including genetic mutations (e.g., IRF6 and MSX1), micronutrient deficiencies (folate and vitamin A), and exposure to teratogenic substances such as tobacco and pesticides. Early detection using 3D ultrasound was found to be effective for prenatal identification. Optimal management requires a multidisciplinary approach involving surgical intervention, speech therapy, and psychosocial support for both the child and their family. The study concludes by underscoring the importance of cross-sector collaboration in promoting comprehensive prevention and management strategies, as well as the need to ensure equitable access to healthcare services and public education to improve the quality of life for individuals affected by palatoschisis.
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References
Afra Hafizh A, Atifah Yusni 2021,’Article Review: Analysis of Patients with Labioschisis or Cleft Lip Review Artikel: Analisis Penderita Labioschisis atau Bibir Sumbing’. Prosiding SEMNAS BIO 2021Universitas Negeri Padang ISSN: 2809-8447
Garcia, M. and Lopez, R., 2018. Maternal Nutrition and Orofacial Clefts. International Journal of Nutrition.
Kumar, V., Sharma, D., and Patel, K., 2020. Multidisciplinary Management of Cleft Palate.
Journal of Pediatric Surgery.
Kurnia Aifa, Fadhilah Hafizah., Atifah Yusni 2023,’Literature Review: Malforasi Cleft Lip (Bibir Sumbing) Pada Bayi’. Prosiding SEMNAS BIO 2023 UIN Raden Fatah Palembang ISSN: 2809-8447
Lee, C., Wong, H., and Tan, S., 2018. Epidemiology of Orofacial Clefts in Asia. Asian Journal of Pediatrics.
Mendoza, P., Alvarez, J., and Franco, L., 2017. Surgical Techniques in Cleft Palate Repair. OMFS Today.
Nakamura, K., Ito, M., and Yoshida, N., 2022. Speech Development in Children with Cleft Palate. Pediatric Rehabilitation.
Puspita Rika D, Fitriyani Dini.,Atifah Yusni 2023,’Literature Review: Pengaruh Paparan Asap Rokok Dan kondisi Ibu Hamil Terhadap Kelahiran Anak Bibir Sumbing (Cleft Lip)’. Prosiding SEMNAS BIO 2023 UIN Raden Fatah Palembang ISSN: 2809-8447
Rahman, A. and Devi, L., 2019. Cleft Palate Detection via Prenatal Imaging. Prenatal Diagnostics.
Smith, J., Anderson, B., and Clark, H., 2020. The Etiology and Risk Factors of Cleft Palate. Journal of Craniofacial Genetics.
Tanaka, M. and Suzuki, T., 2021. Genetic Polymorphisms in CLP Cases. Molecular Human Genetics.
Wilson, H. and Green, T., 2023. Parental Counseling for Cleft Conditions. Family Health Quarterly.
Yuandry Syafrina, Dewi Rahmawitra C,Atifah Yusni 2023,’Literatur Review: Pengaruh Konsumsi Asam Folat Bagi Ibu Hamil Terhadap Kelahiran Anak Dengan Kelainan Kongenital’. Prosiding SEMNAS BIO 2023 UIN Raden Fatah Palembang ISSN: 2809-8447
Yulita Nelfi, Atifah Yusni 2021,’Pengaruh Ibu sebagai Penderita Diabetes Mellitus terhadap Resiko Kelahiran Cleft Lip dan Palate’. Prosiding SEMNAS BIO 2021 Universitas Negeri Padang ISSN: 2809-8447
Zhang, X., Liu, Y., Chen, M., and Wang, H., 2021. Environmental Teratogens and Facial Malformations. Teratology Reports.