Evaluation of Antibacterial Activity and Toxicity Effects of Newbouldia Stem Bark Extract
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Page Numbers:
12-22
Digital Object Identifier:
10.58578/ajbmbr.v1i1.3350
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Authors:Kerenhappuch Isaac Umaru1, Isaac John Umaru2, Akafa Andes Tansaba3, Chakfa Nanmar4, Egeonu Stephen Ugoeze5
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Abstract
Newbouldia leavis is a boundary tree. it is a medium size angiosperm which belongs to the Bignoniaceae family. It is a fast-growing evergreen shrub or small tree. This study was carried out to investigate antibacterial activity of the methanol extract of Newbouldia stem bark. The antibacterial activity of the methanol extracts was determined by the agar well diffusion method. Three standard bacterial strains: Escherichia coli, Staphylococcus aureus, and Klebsiella pneumoniae were used for the antibacterial assay. Result of screening plant extracts for antibacterial activity showed that most of the organisms were sensitive to the extract. The antibacterial test utilizing well diffusion assay showed that Gram-positive bacteria were more susceptible to the plant extract compared to Gram-negative bacteria. This study supports the use of Newboulda leavis in traditional medicine as well as highlights the need to further explore the potentials of the plant extract as antibacterial agent.
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Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.