Synthesis, Characterizations and Biological Efficacy of Aminobenzofuran and 2-Methoxyphenylacetaldehyde and Its Co(II) and Zn(II) Complexes

Page Numbers: 589-599
Published: 2024-07-31
Digital Object Identifier: 10.58578/amjsai.v1i1.3738
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  • Abduljeleel Mohd Abdulazeez Kano University of Science and Technology Wudil, Kano State, Nigeria
  • Ahmad Aminu Kano University of Science and Technology Wudil, Kano State, Nigeria
  • Aisha Ahmad Kano University of Science and Technology Wudil, Kano State, Nigeria

Abstract

Metal complexes of some transition metal ions viz Co (II), and Zn (II) have been synthesized from a Schiff base (L) formed by the condensation of 2-amino-benzofuran and 2-methoxyphenylacetaldehyde. Synthesized compounds have been studied by various spectroscopic techniques and eval_uated for their biological efficacy. From the FTIR result, A peak at 1566 cm-1 was assigned to azomethine v(C=N) stretching vibration, which shifted to 1640cm-1 and 1637cm-1 in cobalt (II) and, zinc (II) complexes respectively. Also, a broad band was observed in the Schiff base and the complexes at 3219cm-1 which indicate presence of water of crystallization to the complex structure. The complexes are non-electrolytic in nature and have high thermal stability. Job’s method of continuous variation suggests 1:2 metal to ligand ratio. Antibacterial and antifungal study of ligand and its metal complexes have shown that the metal complexes are more active than their corresponding ligand.

Keywords: Aminobenzofuran; 2-Methoxyphenylacetaldehyde; Ligand; Characterization
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Abdulazeez, A. M., Aminu, A., & Ahmad, A. (2024). Synthesis, Characterizations and Biological Efficacy of Aminobenzofuran and 2-Methoxyphenylacetaldehyde and Its Co(II) and Zn(II) Complexes. African Multidisciplinary Journal of Sciences and Artificial Intelligence, 1(1), 589-599. https://doi.org/10.58578/amjsai.v1i1.3738

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